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Evidence for a Role of Endocannabinoids, Astrocytes and p38 Phosphorylation in the Resolution of Postoperative Pain
BACKGROUND: An alarming portion of patients develop persistent or chronic pain following surgical procedures, but the mechanisms underlying the transition from acute to chronic pain states are not fully understood. In general, endocannabinoids (ECBs) inhibit nociceptive processing by stimulating can...
Autores principales: | Alkaitis, Matthew S., Solorzano, Carlos, Landry, Russell P., Piomelli, Daniele, DeLeo, Joyce A., Romero-Sandoval, E. Alfonso |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2878341/ https://www.ncbi.nlm.nih.gov/pubmed/20531936 http://dx.doi.org/10.1371/journal.pone.0010891 |
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