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Bare Bones Pattern Formation: A Core Regulatory Network in Varying Geometries Reproduces Major Features of Vertebrate Limb Development and Evolution

BACKGROUND: Major unresolved questions regarding vertebrate limb development concern how the numbers of skeletal elements along the proximodistal (P-D) and anteroposterior (A-P) axes are determined and how the shape of a growing limb affects skeletal element formation. There is currently no generall...

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Detalles Bibliográficos
Autores principales: Zhu, Jianfeng, Zhang, Yong-Tao, Alber, Mark S., Newman, Stuart A.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2878345/
https://www.ncbi.nlm.nih.gov/pubmed/20531940
http://dx.doi.org/10.1371/journal.pone.0010892