Derepression of CLDN3 and CLDN4 during ovarian tumorigenesis is associated with loss of repressive histone modifications

Unlike epigenetic silencing of tumor suppressor genes, the role of epigenetic derepression of cancer-promoting genes or oncogenes in carcinogenesis remains less well understood. The tight junction proteins claudin-3 and claudin-4 are frequently overexpressed in ovarian cancer and their overexpressio...

Descripción completa

Detalles Bibliográficos
Autores principales: Kwon, Mi Jeong, Kim, Sung-Su, Choi, Yoon-La, Jung, Hun Soon, Balch, Curt, Kim, Su-Hyeong, Song, Yong-Sang, Marquez, Victor E., Nephew, Kenneth P., Shin, Young Kee
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2010
Materias:
Cancer Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2878357/
https://www.ncbi.nlm.nih.gov/pubmed/20053926
http://dx.doi.org/10.1093/carcin/bgp336

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2878357/
https://www.ncbi.nlm.nih.gov/pubmed/20053926
http://dx.doi.org/10.1093/carcin/bgp336

Ejemplares similares