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Src kinase activation is mandatory for MDA-9/syntenin-mediated activation of Nuclear Factor-κB
The scaffolding PDZ-domain containing protein MDA-9/syntenin is a tandem PDZ protein overexpressed in human melanoma, and breast and gastric cancer cells. MDA-9/syntenin affects cancer cell motility and invasion through distinct biochemical and signaling pathways, including focal adhesion kinase (FA...
Autores principales: | , , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2878370/ https://www.ncbi.nlm.nih.gov/pubmed/20228839 http://dx.doi.org/10.1038/onc.2010.65 |