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Src kinase activation is mandatory for MDA-9/syntenin-mediated activation of Nuclear Factor-κB

The scaffolding PDZ-domain containing protein MDA-9/syntenin is a tandem PDZ protein overexpressed in human melanoma, and breast and gastric cancer cells. MDA-9/syntenin affects cancer cell motility and invasion through distinct biochemical and signaling pathways, including focal adhesion kinase (FA...

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Detalles Bibliográficos
Autores principales: Boukerche, H., Aissaoui, H., Prévost, C., Hirbec, H., Das, S. K., Su, Z.-z., Sarkar, D., Fisher, P. B.
Formato: Texto
Lenguaje:English
Publicado: 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2878370/
https://www.ncbi.nlm.nih.gov/pubmed/20228839
http://dx.doi.org/10.1038/onc.2010.65