SSBP2 is an in vivo tumor suppressor and regulator of LDB1 stability

SSBP proteins bind and stabilize transcriptional cofactor Lim Domain Binding protein1 (LDB1) from proteosomal degradation to promote tissue specific transcription through an evolutionarily conserved pathway. The human SSBP2 gene was isolated as a candidate tumor suppressor from a critical region of...

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Detalles Bibliográficos
Autores principales: Wang, Yang, Klumpp, Sherry, Amin, Hesham M., Liang, Hong, Li, June, Estrov, Zeev, Zweidler-McKay, Patrick, Brandt, Stephen J., Agulnick, Alan, Nagarajan, Lalitha
Formato: Texto
Lenguaje:English
Publicado: 2010
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2878399/
https://www.ncbi.nlm.nih.gov/pubmed/20348955
http://dx.doi.org/10.1038/onc.2010.78

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2878399/
https://www.ncbi.nlm.nih.gov/pubmed/20348955
http://dx.doi.org/10.1038/onc.2010.78

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