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Multiple mechanisms collectively regulate clathrin-mediated endocytosis of the epidermal growth factor receptor

Endocytosis of the epidermal growth factor receptor (EGFR) is important for the regulation of EGFR signaling. However, EGFR endocytosis mechanisms are poorly understood, which precludes development of approaches to specifically inhibit EGFR endocytosis and analyze its impact on signaling. Using a co...

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Detalles Bibliográficos
Autores principales: Goh, Lai Kuan, Huang, Fangtian, Kim, Woong, Gygi, Steven, Sorkin, Alexander
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2878939/
https://www.ncbi.nlm.nih.gov/pubmed/20513767
http://dx.doi.org/10.1083/jcb.201001008