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The role of UDP-Glc:glycoprotein glucosyltransferase 1 in the maturation of an obligate substrate prosaposin

An endoplasmic reticulum (ER) quality control system assists in efficient folding and disposal of misfolded proteins. N-linked glycans are critical in these events because their composition dictates interactions with molecular chaperones. UDP-glucose:glycoprotein glucosyltransferase 1 (UGT1) is a ke...

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Detalles Bibliográficos
Autores principales: Pearse, Bradley R., Tamura, Taku, Sunryd, Johan C., Grabowski, Gregory A., Kaufman, Randal J., Hebert, Daniel N.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2878942/
https://www.ncbi.nlm.nih.gov/pubmed/20498017
http://dx.doi.org/10.1083/jcb.200912105