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Nebulin regulates actin filament lengths by a stabilization mechanism

Efficient muscle contraction requires regulation of actin filament lengths. In one highly cited model, the giant protein nebulin has been proposed to function as a molecular ruler specifying filament lengths. We directly challenged this hypothesis by constructing a unique, small version of nebulin (...

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Detalles Bibliográficos
Autores principales: Pappas, Christopher T., Krieg, Paul A., Gregorio, Carol C.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2878950/
https://www.ncbi.nlm.nih.gov/pubmed/20498015
http://dx.doi.org/10.1083/jcb.201001043