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Nebulin regulates actin filament lengths by a stabilization mechanism
Efficient muscle contraction requires regulation of actin filament lengths. In one highly cited model, the giant protein nebulin has been proposed to function as a molecular ruler specifying filament lengths. We directly challenged this hypothesis by constructing a unique, small version of nebulin (...
Autores principales: | Pappas, Christopher T., Krieg, Paul A., Gregorio, Carol C. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2878950/ https://www.ncbi.nlm.nih.gov/pubmed/20498015 http://dx.doi.org/10.1083/jcb.201001043 |
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