Creating PWMs of transcription factors using 3D structure-based computation of protein-DNA free binding energies

BACKGROUND: Knowledge of transcription factor-DNA binding patterns is crucial for understanding gene transcription. Numerous DNA-binding proteins are annotated as transcription factors in the literature, however, for many of them the corresponding DNA-binding motifs remain uncharacterized. RESULTS:...

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Detalles Bibliográficos
Autores principales: Alamanova, Denitsa, Stegmaier, Philip, Kel, Alexander
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Research article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2879287/
https://www.ncbi.nlm.nih.gov/pubmed/20438625
http://dx.doi.org/10.1186/1471-2105-11-225

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2879287/
https://www.ncbi.nlm.nih.gov/pubmed/20438625
http://dx.doi.org/10.1186/1471-2105-11-225

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