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Creating PWMs of transcription factors using 3D structure-based computation of protein-DNA free binding energies
BACKGROUND: Knowledge of transcription factor-DNA binding patterns is crucial for understanding gene transcription. Numerous DNA-binding proteins are annotated as transcription factors in the literature, however, for many of them the corresponding DNA-binding motifs remain uncharacterized. RESULTS:...
Autores principales: | Alamanova, Denitsa, Stegmaier, Philip, Kel, Alexander |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2879287/ https://www.ncbi.nlm.nih.gov/pubmed/20438625 http://dx.doi.org/10.1186/1471-2105-11-225 |
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