MixHMM: Inferring Copy Number Variation and Allelic Imbalance Using SNP Arrays and Tumor Samples Mixed with Stromal Cells

BACKGROUND: Genotyping platforms such as single nucleotide polymorphism (SNP) arrays are powerful tools to study genomic aberrations in cancer samples. Allele specific information from SNP arrays provides valuable information for interpreting copy number variation (CNV) and allelic imbalance includi...

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Detalles Bibliográficos
Autores principales: Liu, Zongzhi, Li, Ao, Schulz, Vincent, Chen, Min, Tuck, David
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2879364/
https://www.ncbi.nlm.nih.gov/pubmed/20532221
http://dx.doi.org/10.1371/journal.pone.0010909

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2879364/
https://www.ncbi.nlm.nih.gov/pubmed/20532221
http://dx.doi.org/10.1371/journal.pone.0010909

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