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MixHMM: Inferring Copy Number Variation and Allelic Imbalance Using SNP Arrays and Tumor Samples Mixed with Stromal Cells
BACKGROUND: Genotyping platforms such as single nucleotide polymorphism (SNP) arrays are powerful tools to study genomic aberrations in cancer samples. Allele specific information from SNP arrays provides valuable information for interpreting copy number variation (CNV) and allelic imbalance includi...
Autores principales: | Liu, Zongzhi, Li, Ao, Schulz, Vincent, Chen, Min, Tuck, David |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2879364/ https://www.ncbi.nlm.nih.gov/pubmed/20532221 http://dx.doi.org/10.1371/journal.pone.0010909 |
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