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Human Complement Regulators C4b-Binding Protein and C1 Esterase Inhibitor Interact with a Novel Outer Surface Protein of Borrelia recurrentis

The spirochete Borrelia recurrentis is the causal agent of louse-borne relapsing fever and is transmitted to humans by the infected body louse Pediculus humanus. We have recently demonstrated that the B. recurrentis surface receptor, HcpA, specifically binds factor H, the regulator of the alternativ...

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Detalles Bibliográficos
Autores principales: Grosskinsky, Sonja, Schott, Melanie, Brenner, Christiane, Cutler, Sally J., Simon, Markus M., Wallich, Reinhard
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2879370/
https://www.ncbi.nlm.nih.gov/pubmed/20532227
http://dx.doi.org/10.1371/journal.pntd.0000698