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Dynamic Assignment and Maintenance of Positional Identity in the Ventral Neural Tube by the Morphogen Sonic Hedgehog

Morphogens are secreted signalling molecules that act in a graded manner to control the pattern of cellular differentiation in developing tissues. An example is Sonic hedgehog (Shh), which acts in several developing vertebrate tissues, including the central nervous system, to provide positional info...

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Detalles Bibliográficos
Autores principales: Dessaud, Eric, Ribes, Vanessa, Balaskas, Nikolaos, Yang, Lin Lin, Pierani, Alessandra, Kicheva, Anna, Novitch, Bennett G., Briscoe, James, Sasai, Noriaki
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2879390/
https://www.ncbi.nlm.nih.gov/pubmed/20532235
http://dx.doi.org/10.1371/journal.pbio.1000382