Crystal structures of Saccharomyces cerevisiae tryptophanyl-tRNA synthetase: new insights into the mechanism of tryptophan activation and implications for anti-fungal drug design

Specific activation of amino acids by aminoacyl-tRNA synthetases is essential for maintaining translational fidelity. Here, we present crystal structures of Saccharomyces cerevisiae tryptophanyl-tRNA synthetase (sTrpRS) in apo form and in complexes with various ligands. In each complex, there is a s...

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Detalles Bibliográficos
Autores principales: Zhou, Minyun, Dong, Xianchi, Shen, Ning, Zhong, Chen, Ding, Jianping
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2010
Materias:
Structural Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2879500/
https://www.ncbi.nlm.nih.gov/pubmed/20123733
http://dx.doi.org/10.1093/nar/gkp1254

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2879500/
https://www.ncbi.nlm.nih.gov/pubmed/20123733
http://dx.doi.org/10.1093/nar/gkp1254

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