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A measure of bending in nucleic acids structures applied to A-tract DNA

A method is proposed to measure global bending in DNA and RNA structures. It relies on a properly defined averaging of base-fixed coordinate frames, computes mean frames of suitably chosen groups of bases and uses these mean frames to evaluate bending. The method is applied to DNA A-tracts, known to...

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Detalles Bibliográficos
Autores principales: Lankaš, F., Špačková, N., Moakher, M., Enkhbayar, P., Šponer, J.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2879501/
https://www.ncbi.nlm.nih.gov/pubmed/20123729
http://dx.doi.org/10.1093/nar/gkq001