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The DNA binding CXC domain of MSL2 is required for faithful targeting the Dosage Compensation Complex to the X chromosome

Dosage compensation in Drosophila melanogaster involves the selective targeting of the male X chromosome by the dosage compensation complex (DCC) and the coordinate, ∼2-fold activation of most genes. The principles that allow the DCC to distinguish the X chromosome from the autosomes are not underst...

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Detalles Bibliográficos
Autores principales: Fauth, Torsten, Müller-Planitz, Felix, König, Cornelia, Straub, Tobias, Becker, Peter B.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2879509/
https://www.ncbi.nlm.nih.gov/pubmed/20139418
http://dx.doi.org/10.1093/nar/gkq026