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Force spectroscopy and fluorescence microscopy of dsDNA–YOYO-1 complexes: implications for the structure of dsDNA in the overstretching region

When individual dsDNA molecules are stretched beyond their B-form contour length, they reveal a structural transition in which the molecule extends 1.7 times its contour length. The nature of this transition is still a subject of debate. In the first model, the DNA helix unwinds and combined with th...

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Detalles Bibliográficos
Autores principales: Murade, Chandrashekhar U., Subramaniam, Vinod, Otto, Cees, Bennink, Martin L.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2879515/
https://www.ncbi.nlm.nih.gov/pubmed/20129944
http://dx.doi.org/10.1093/nar/gkq034