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Strong dependence between functional domains in a dual-function snoRNA infers coupling of rRNA processing and modification events

Most small nucleolar RNAs (snoRNAs) guide rRNA nucleotide modifications, some participate in pre-rRNA cleavages, and a few have both functions. These activities involve direct base-pairing of the snoRNA with pre-rRNA using different domains. It is not known if the modification and processing functio...

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Detalles Bibliográficos
Autores principales: Liang, Xue-hai, Liu, Qing, Liu, Quansheng, King, Thomas H., Fournier, Maurille J.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2010
Materias:
RNA
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2879522/
https://www.ncbi.nlm.nih.gov/pubmed/20144950
http://dx.doi.org/10.1093/nar/gkq043