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Boosting the prediction and understanding of DNA-binding domains from sequence

DNA-binding proteins perform vital functions related to transcription, repair and replication. We have developed a new sequence-based machine learning protocol to identify DNA-binding proteins. We compare our method with an extensive benchmark of previously published structure-based machine learning...

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Detalles Bibliográficos
Autores principales: Langlois, Robert E., Lu, Hui
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2879530/
https://www.ncbi.nlm.nih.gov/pubmed/20156993
http://dx.doi.org/10.1093/nar/gkq061