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Trichostatin A enhances acetylation as well as protein stability of ERα through induction of p300 protein

INTRODUCTION: Trichostatin A (TSA) is a well-characterized histone deacetylase (HDAC) inhibitor. TSA modifies the balance between HDAC and histone acetyltransferase activities that is important in chromatin remodeling and gene expression. Although several previous studies have demonstrated the role...

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Detalles Bibliográficos
Autores principales: Kim, Sung-Hye, Kang, Hyun-Jin, Na, Hyelin, Lee, Mi-Ock
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2879569/
https://www.ncbi.nlm.nih.gov/pubmed/20388208
http://dx.doi.org/10.1186/bcr2562