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Trichostatin A enhances acetylation as well as protein stability of ERα through induction of p300 protein
INTRODUCTION: Trichostatin A (TSA) is a well-characterized histone deacetylase (HDAC) inhibitor. TSA modifies the balance between HDAC and histone acetyltransferase activities that is important in chromatin remodeling and gene expression. Although several previous studies have demonstrated the role...
Autores principales: | , , , |
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Formato: | Texto |
Lenguaje: | English |
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BioMed Central
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2879569/ https://www.ncbi.nlm.nih.gov/pubmed/20388208 http://dx.doi.org/10.1186/bcr2562 |