Emergence of rationally designed therapeutic strategies for breast cancer targeting DNA repair mechanisms

Accumulating evidence suggests that many cancers, including BRCA1- and BRCA2-associated breast cancers, are deficient in DNA repair processes. Both hereditary and sporadic breast cancers have been found to have significant downregulation of repair factors. This has provided opportunities to exploit...

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Detalles Bibliográficos
Autores principales: Rowe, Bryan P, Glazer, Peter M
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2879573/
https://www.ncbi.nlm.nih.gov/pubmed/20459590
http://dx.doi.org/10.1186/bcr2566

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2879573/
https://www.ncbi.nlm.nih.gov/pubmed/20459590
http://dx.doi.org/10.1186/bcr2566

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