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Emergence of rationally designed therapeutic strategies for breast cancer targeting DNA repair mechanisms
Accumulating evidence suggests that many cancers, including BRCA1- and BRCA2-associated breast cancers, are deficient in DNA repair processes. Both hereditary and sporadic breast cancers have been found to have significant downregulation of repair factors. This has provided opportunities to exploit...
Autores principales: | Rowe, Bryan P, Glazer, Peter M |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2879573/ https://www.ncbi.nlm.nih.gov/pubmed/20459590 http://dx.doi.org/10.1186/bcr2566 |
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