The Role of Nucleotide Excision by Reverse Transcriptase in HIV Drug Resistance

Nucleoside reverse transcriptase (RT) inhibitors of HIV block viral replication through the ability of HIV RT to incorporate chain-terminating nucleotide analogs during viral DNA synthesis. Once incorporated, the chain-terminating residue must be removed before DNA synthesis can continue. Removal ca...

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Detalles Bibliográficos
Autores principales: Acosta-Hoyos, Antonio J., Scott, Walter A.
Formato: Texto
Lenguaje:English
Publicado: Molecular Diversity Preservation International (MDPI) 2010
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2879589/
https://www.ncbi.nlm.nih.gov/pubmed/20523911
http://dx.doi.org/10.3390/v2020372

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2879589/
https://www.ncbi.nlm.nih.gov/pubmed/20523911
http://dx.doi.org/10.3390/v2020372

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