G domain dimerization controls dynamin's assembly-stimulated GTPase activity

Dynamin is an atypical GTPase that catalyzes membrane fission during clathrin-mediated endocytosis. The mechanisms of dynamin’s basal and assembly-stimulated GTP hydrolysis are unknown, though both are indirectly influenced by the GTPase effector domain (GED). Here we present the 2.0Å resolution cry...

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Detalles Bibliográficos
Autores principales: Chappie, Joshua S., Acharya, Sharmistha, Leonard, Marilyn, Schmid, Sandra L., Dyda, Fred
Formato: Texto
Lenguaje:English
Publicado: 2010
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2879890/
https://www.ncbi.nlm.nih.gov/pubmed/20428113
http://dx.doi.org/10.1038/nature09032

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2879890/
https://www.ncbi.nlm.nih.gov/pubmed/20428113
http://dx.doi.org/10.1038/nature09032

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