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Systematic calibration of a cell signaling network model

BACKGROUND: Mathematical modeling is being applied to increasingly complex biological systems and datasets; however, the process of analyzing and calibrating against experimental data is often challenging and a rate limiting step in model development. To address this problem, we developed a systemat...

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Detalles Bibliográficos
Autores principales: Kim, Kyoung Ae, Spencer, Sabrina L, Albeck, John G, Burke, John M, Sorger, Peter K, Gaudet, Suzanne, Kim, Do Hyun
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2880028/
https://www.ncbi.nlm.nih.gov/pubmed/20416044
http://dx.doi.org/10.1186/1471-2105-11-202