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Lethal mutagenesis and evolutionary epidemiology
The lethal mutagenesis hypothesis states that within-host populations of pathogens can be driven to extinction when the load of deleterious mutations is artificially increased with a mutagen, and becomes too high for the population to be maintained. Although chemical mutagens have been shown to lead...
| Autores principales: | , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
The Royal Society
2010
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2880112/ https://www.ncbi.nlm.nih.gov/pubmed/20478890 http://dx.doi.org/10.1098/rstb.2010.0058 |