Positive selection of DNA-protein interactions in mammalian cells through phenotypic coupling with retrovirus production

Through the shuffling of predefined modular zinc finger (ZF) domains with predictable target site recognition in vitro, we have generated a large repertoire of artificial transcription factors (ATFs) with five ZF domains (TF(ZF)s). Here we report an effective strategy for the selection of ATF librar...

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Detalles Bibliográficos
Autores principales: Tschulena, Ulrich, Peterson, Kenneth R., Gonzalez, Beatriz, Fedosyuk, Halyna, Barbas, Carlos F.
Formato: Texto
Lenguaje:English
Publicado: 2009
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2880176/
https://www.ncbi.nlm.nih.gov/pubmed/19838191
http://dx.doi.org/10.1038/nsmb.1677

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2880176/
https://www.ncbi.nlm.nih.gov/pubmed/19838191
http://dx.doi.org/10.1038/nsmb.1677

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