Review: Bilirubin pKa studies; new models and theories indicate high pKa values in water, dimethylformamide and DMSO

BACKGROUND: Correct aqueous pKa values of unconjugated bilirubin (UCB), a poorly-soluble, unstable substance, are essential for understanding its functions. Our prior solvent partition studies, of unlabeled and [(14)C] UCB, indicated pKa values above 8.0. These high values were attributed to effects...

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Detalles Bibliográficos
Autores principales: Mukerjee, Pasupati, Ostrow, J Donald
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Research article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2880415/
https://www.ncbi.nlm.nih.gov/pubmed/20350305
http://dx.doi.org/10.1186/1471-2091-11-15

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2880415/
https://www.ncbi.nlm.nih.gov/pubmed/20350305
http://dx.doi.org/10.1186/1471-2091-11-15

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