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Type I gamma phosphatidylinositol phosphate kinase modulates invasion and proliferation and its expression correlates with poor prognosis in breast cancer

INTRODUCTION: The loss of E-cadherin based cell-cell contacts and tumor cell migration to the vasculature and lymphatic system are hallmarks of metastasis of epithelial cancers. Type I gamma phosphatidylinositol phosphate kinase (PIPKIγ), an enzyme that generates phosphatidylinositol 4,5-bisphosphat...

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Detalles Bibliográficos
Autores principales: Sun, Yue, Turbin, Dmitry A, Ling, Kun, Thapa, Narendra, Leung, Samuel, Huntsman, David G, Anderson, Richard A
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2880426/
https://www.ncbi.nlm.nih.gov/pubmed/20074374
http://dx.doi.org/10.1186/bcr2471