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Type I gamma phosphatidylinositol phosphate kinase modulates invasion and proliferation and its expression correlates with poor prognosis in breast cancer
INTRODUCTION: The loss of E-cadherin based cell-cell contacts and tumor cell migration to the vasculature and lymphatic system are hallmarks of metastasis of epithelial cancers. Type I gamma phosphatidylinositol phosphate kinase (PIPKIγ), an enzyme that generates phosphatidylinositol 4,5-bisphosphat...
Autores principales: | Sun, Yue, Turbin, Dmitry A, Ling, Kun, Thapa, Narendra, Leung, Samuel, Huntsman, David G, Anderson, Richard A |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2880426/ https://www.ncbi.nlm.nih.gov/pubmed/20074374 http://dx.doi.org/10.1186/bcr2471 |
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