Promotion of variant human mammary epithelial cell outgrowth by ionizing radiation: an agent-based model supported by in vitro studies

INTRODUCTION: Most human mammary epithelial cells (HMEC) cultured from histologically normal breast tissues enter a senescent state termed stasis after 5 to 20 population doublings. These senescent cells display increased size, contain senescence associated β-galactosidase activity, and express cycl...

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Detalles Bibliográficos
Autores principales: Mukhopadhyay, Rituparna, Costes, Sylvain V, Bazarov, Alexey V, Hines, William C, Barcellos-Hoff, Mary Helen, Yaswen, Paul
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Research article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2880432/
https://www.ncbi.nlm.nih.gov/pubmed/20146798
http://dx.doi.org/10.1186/bcr2477

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2880432/
https://www.ncbi.nlm.nih.gov/pubmed/20146798
http://dx.doi.org/10.1186/bcr2477

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