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Promotion of variant human mammary epithelial cell outgrowth by ionizing radiation: an agent-based model supported by in vitro studies
INTRODUCTION: Most human mammary epithelial cells (HMEC) cultured from histologically normal breast tissues enter a senescent state termed stasis after 5 to 20 population doublings. These senescent cells display increased size, contain senescence associated β-galactosidase activity, and express cycl...
Autores principales: | Mukhopadhyay, Rituparna, Costes, Sylvain V, Bazarov, Alexey V, Hines, William C, Barcellos-Hoff, Mary Helen, Yaswen, Paul |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2880432/ https://www.ncbi.nlm.nih.gov/pubmed/20146798 http://dx.doi.org/10.1186/bcr2477 |
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