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The CFTR Met 470 Allele Is Associated with Lower Birth Rates in Fertile Men from a Population Isolate

Although little is known about the role of the cystic fibrosis transmembrane regulator (CFTR) gene in reproductive physiology, numerous variants in this gene have been implicated in etiology of male infertility due to congenital bilateral absence of the vas deferens (CBAVD). Here, we studied the fer...

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Detalles Bibliográficos
Autores principales: Kosova, Gülüm, Pickrell, Joseph K., Kelley, Joanna L., McArdle, Patrick F., Shuldiner, Alan R., Abney, Mark, Ober, Carole
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2880556/
https://www.ncbi.nlm.nih.gov/pubmed/20532200
http://dx.doi.org/10.1371/journal.pgen.1000974