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Use of Genome-Wide Expression Data to Mine the “Gray Zone” of GWA Studies Leads to Novel Candidate Obesity Genes

To get beyond the “low-hanging fruits” so far identified by genome-wide association (GWA) studies, new methods must be developed in order to discover the numerous remaining genes that estimates of heritability indicate should be contributing to complex human phenotypes, such as obesity. Here we desc...

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Detalles Bibliográficos
Autores principales: Naukkarinen, Jussi, Surakka, Ida, Pietiläinen, Kirsi H., Rissanen, Aila, Salomaa, Veikko, Ripatti, Samuli, Yki-Järvinen, Hannele, van Duijn, Cornelia M., Wichmann, H.-Erich, Kaprio, Jaakko, Taskinen, Marja-Riitta, Peltonen, Leena
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2880558/
https://www.ncbi.nlm.nih.gov/pubmed/20532202
http://dx.doi.org/10.1371/journal.pgen.1000976