The SOCS-Box of HIV-1 Vif Interacts with ElonginBC by Induced-Folding to Recruit Its Cul5-Containing Ubiquitin Ligase Complex

The HIV-1 viral infectivity factor (Vif) protein recruits an E3 ubiquitin ligase complex, comprising the cellular proteins elongin B and C (EloBC), cullin 5 (Cul5) and RING-box 2 (Rbx2), to the anti-viral proteins APOBEC3G (A3G) and APOBEC3F (A3F) and induces their polyubiquitination and proteasomal...

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Detalles Bibliográficos
Autores principales: Bergeron, Julien R. C., Huthoff, Hendrik, Veselkov, Dennis A., Beavil, Rebecca L., Simpson, Peter J., Matthews, Stephen J., Malim, Michael H., Sanderson, Mark R.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2880568/
https://www.ncbi.nlm.nih.gov/pubmed/20532212
http://dx.doi.org/10.1371/journal.ppat.1000925

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2880568/
https://www.ncbi.nlm.nih.gov/pubmed/20532212
http://dx.doi.org/10.1371/journal.ppat.1000925

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