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beta-Catenin Regulates Intercellular Signalling Networks and Cell-Type Specific Transcription in the Developing Mouse Midbrain-Rhombomere 1 Region

β-catenin is a multifunctional protein involved in both signalling by secreted factors of Wnt family and regulation of the cellular architecture. We show that β-catenin stabilization in mouse midbrain-rhombomere1 region leads to robust up-regulation of several Wnt signalling target genes, including...

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Detalles Bibliográficos
Autores principales: Chilov, Dmitri, Sinjushina, Natalia, Saarimäki-Vire, Jonna, Taketo, Makoto M., Partanen, Juha
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2880587/
https://www.ncbi.nlm.nih.gov/pubmed/20532162
http://dx.doi.org/10.1371/journal.pone.0010881