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beta-Catenin Regulates Intercellular Signalling Networks and Cell-Type Specific Transcription in the Developing Mouse Midbrain-Rhombomere 1 Region
β-catenin is a multifunctional protein involved in both signalling by secreted factors of Wnt family and regulation of the cellular architecture. We show that β-catenin stabilization in mouse midbrain-rhombomere1 region leads to robust up-regulation of several Wnt signalling target genes, including...
Autores principales: | Chilov, Dmitri, Sinjushina, Natalia, Saarimäki-Vire, Jonna, Taketo, Makoto M., Partanen, Juha |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2880587/ https://www.ncbi.nlm.nih.gov/pubmed/20532162 http://dx.doi.org/10.1371/journal.pone.0010881 |
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