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Splicing Reporter Mice Revealed the Evolutionally Conserved Switching Mechanism of Tissue-Specific Alternative Exon Selection

Since alternative splicing of pre-mRNAs is essential for generating tissue-specific diversity in proteome, elucidating its regulatory mechanism is indispensable to understand developmental process or tissue-specific functions. We have been focusing on tissue-specific regulation of mutually exclusive...

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Detalles Bibliográficos
Autores principales: Takeuchi, Akihide, Hosokawa, Motoyasu, Nojima, Takayuki, Hagiwara, Masatoshi
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2880598/
https://www.ncbi.nlm.nih.gov/pubmed/20532173
http://dx.doi.org/10.1371/journal.pone.0010946