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An Assay to Monitor HIV-1 Protease Activity for the Identification of Novel Inhibitors in T-Cells

The emergence of resistant HIV strains, together with the severe side-effects of existing drugs and lack of development of effective anti-HIV vaccines highlight the need for novel antivirals, as well as innovative methods to facilitate their discovery. Here, we have developed an assay in T-cells to...

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Detalles Bibliográficos
Autores principales: Hilton, Brett J., Wolkowicz, Roland
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2880603/
https://www.ncbi.nlm.nih.gov/pubmed/20532177
http://dx.doi.org/10.1371/journal.pone.0010940