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Solution Structure and Characterisation of the Human Pyruvate Dehydrogenase Complex Core Assembly
Mammalian pyruvate dehydrogenase complex (PDC) is a key multi-enzyme assembly that is responsible for glucose homeostasis maintenance and conversion of pyruvate into acetyl-CoA. It comprises a central pentagonal dodecahedral core consisting of two subunit types (E2 and E3BP) to which peripheral enzy...
Autores principales: | , , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2880790/ https://www.ncbi.nlm.nih.gov/pubmed/20361979 http://dx.doi.org/10.1016/j.jmb.2010.03.043 |