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Suppression of Myc oncogenic activity by ribosomal protein haploinsufficiency
The Myc oncogene regulates the expression of multiple components of the protein synthetic machinery, including ribosomal proteins, initiation factors of translation, Pol III, and rDNA1,2. An outstanding question is whether and how increasing the cellular protein synthesis capacity can affect the mul...
Autores principales: | , , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2880952/ https://www.ncbi.nlm.nih.gov/pubmed/19011615 http://dx.doi.org/10.1038/nature07449 |