Utilizing elementary mode analysis, pathway thermodynamics, and a genetic algorithm for metabolic flux determination and optimal metabolic network design

BACKGROUND: Microbial hosts offer a number of unique advantages when used as production systems for both native and heterologous small-molecules. These advantages include high selectivity and benign environmental impact; however, a principal drawback is low yield and/or productivity, which limits ec...

Descripción completa

Detalles Bibliográficos
Autores principales: Boghigian, Brett A, Shi, Hai, Lee, Kyongbum, Pfeifer, Blaine A
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Research article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2880971/
https://www.ncbi.nlm.nih.gov/pubmed/20416071
http://dx.doi.org/10.1186/1752-0509-4-49

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2880971/
https://www.ncbi.nlm.nih.gov/pubmed/20416071
http://dx.doi.org/10.1186/1752-0509-4-49

Ejemplares similares