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Evidence of positive selection at codon sites localized in extracellular domains of mammalian CC motif chemokine receptor proteins

BACKGROUND: CC chemokine receptor proteins (CCR1 through CCR10) are seven-transmembrane G-protein coupled receptors whose signaling pathways are known for their important roles coordinating immune system responses through targeted trafficking of white blood cells. In addition, some of these receptor...

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Detalles Bibliográficos
Autores principales: Metzger, Kelsey J, Thomas, Michael A
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2880985/
https://www.ncbi.nlm.nih.gov/pubmed/20459756
http://dx.doi.org/10.1186/1471-2148-10-139