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Targeting the Neurokinin Receptor 1 with Aprepitant: A Novel Antipruritic Strategy

BACKGROUND: Chronic pruritus is a global clinical problem with a high impact on the quality of life and lack of specific therapies. It is an excruciating and frequent symptom of e.g. uncurable renal, liver and skin diseases which often does not respond to conventional treatment with e.g. antihistami...

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Detalles Bibliográficos
Autores principales: Ständer, Sonja, Siepmann, Dorothee, Herrgott, Ilka, Sunderkötter, Cord, Luger, Thomas A.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2881044/
https://www.ncbi.nlm.nih.gov/pubmed/20532044
http://dx.doi.org/10.1371/journal.pone.0010968