Endocytic pathways mediating oligomeric Aβ42 neurotoxicity

BACKGROUND: One pathological hallmark of Alzheimer's disease (AD) is amyloid plaques, composed primarily of amyloid-β peptide (Aβ). Over-production or diminished clearance of the 42 amino acid form of Aβ (Aβ42) in the brain leads to accumulation of soluble Aβ and plaque formation. Soluble oligo...

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Detalles Bibliográficos
Autores principales: Yu, Chunjiang, Nwabuisi-Heath, Evelyn, Laxton, Kevin, LaDu, Mary Jo
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2881055/
https://www.ncbi.nlm.nih.gov/pubmed/20478062
http://dx.doi.org/10.1186/1750-1326-5-19

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2881055/
https://www.ncbi.nlm.nih.gov/pubmed/20478062
http://dx.doi.org/10.1186/1750-1326-5-19

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