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Endocytic pathways mediating oligomeric Aβ42 neurotoxicity

BACKGROUND: One pathological hallmark of Alzheimer's disease (AD) is amyloid plaques, composed primarily of amyloid-β peptide (Aβ). Over-production or diminished clearance of the 42 amino acid form of Aβ (Aβ42) in the brain leads to accumulation of soluble Aβ and plaque formation. Soluble oligo...

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Detalles Bibliográficos
Autores principales:	Yu, Chunjiang, Nwabuisi-Heath, Evelyn, Laxton, Kevin, LaDu, Mary Jo
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2010
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2881055/ https://www.ncbi.nlm.nih.gov/pubmed/20478062 http://dx.doi.org/10.1186/1750-1326-5-19

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