The inhibitory effect of pyrroloquinoline quinone on the amyloid formation and cytotoxicity of truncated alpha-synuclein

BACKGROUND: Parkinson's disease (PD) involves the selective damage of dopaminergic neuron cells resulting from the accumulation and fibril formation of alpha-synuclein. Recently, it has been shown that not only full-length alpha-synuclein, but also C-terminal truncated forms exist in the normal...

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Detalles Bibliográficos
Autores principales: Kim, Jihoon, Harada, Ryuichi, Kobayashi, Masaki, Kobayashi, Natsuki, Sode, Koji
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2881056/
https://www.ncbi.nlm.nih.gov/pubmed/20482893
http://dx.doi.org/10.1186/1750-1326-5-20

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2881056/
https://www.ncbi.nlm.nih.gov/pubmed/20482893
http://dx.doi.org/10.1186/1750-1326-5-20

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