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Downstream targets of methyl CpG binding protein 2 and their abnormal expression in the frontal cortex of the human Rett syndrome brain

BACKGROUND: The Rett Syndrome (RTT) brain displays regional histopathology and volumetric reduction, with frontal cortex showing such abnormalities, whereas the occipital cortex is relatively less affected. RESULTS: Using microarrays and quantitative PCR, the mRNA expression profiles of these two ne...

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Detalles Bibliográficos
Autores principales: Gibson, Joanne H, Slobedman, Barry, KN, Harikrishnan, Williamson, Sarah L, Minchenko, Dimitri, El-Osta, Assam, Stern, Joshua L, Christodoulou, John
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2881102/
https://www.ncbi.nlm.nih.gov/pubmed/20420693
http://dx.doi.org/10.1186/1471-2202-11-53